c. GC Instrument Components

Students will learn to:
Describe the operational principle of different entry-level techniques such as split/splitless, on column, PTV, thermal desorption-pyrolysis, purge and trap
Differentiate various types of GC sample introduction methods and determine their suitability for specific analytes in different matrices
Interpret the impact of sample introduction on a GC column (particularly on a capillary system) and on the resulting chromatogram from a perspective of how resolution and response for splitless and split injection would be affected.

Students will learn to:
Differentiate different types of columns (i.e., WCOT, PLOT, packed), their dimensions, applicability and diffusion factors affecting the separation
Evaluate suitability of common stationary phases for different analytes
Distinguish types of interactions between the analytes and stationary phase
Justify the selection of a stationary phase based on its interactions, stability, and bleed with the targeted analyte
Evaluate and explain the column bleed

Students will learn to:
Evaluate the suitability of three common detectors (FID, TCD, and ECD) for different analytes
Explain the operation principle of these detectors
Differentiate these detectors in terms of selectivity and other properties (destructive, bulk, concentration/ mass depending) with regard to their suitability for different application